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CONFIRM

ABOUT ACEPODIA

Powerful, Innovative Immune Cell Engager for Patients with Cancer

We are transforming cancer treatment with first-in-class immune cell engager, with enhanced and targeted potency via ACC technology, improved safety and broad applicability across hematologic and solid tumor cancers.  Our cell therapies are designed to offer countless patients a powerful anti-cancer therapeutic option.   

TECHNOLOGY

  • ACC
  • γδ2 T Cells
  • oNK Cells
  • ACC
    TECHNOLOGY

    ACC

    ACC (Antibody-Cell Conjugation) is the Optimized T Cell Engager

    Acepodia is a clinical-stage biotechnology company developing first-in-class cell therapies with its unique Antibody-Cell Conjugation (ACC) platform technology to address gaps in cancer care.
    ACC uses live-cell compatible chemistry to attach tumor-targeting antibodies directly to variety receptors of immune cells enhancing the lock between immune and cancer cells that to generate highly specific, potent cell therapies and can significantly enhance the potency of immune cells, without the need for genetic engineering.
    Leveraging its ACC technology, the company links tumor-targeting antibodies to its proprietary immune cells, such as gamma delta2 T cells to create novel antibody cell effector (ACE) therapies, which have increased binding strength against tumors that express low levels of tumor antigens.

  • γδ2 T Cells
    TECHNOLOGY

    γδ2 T Cells

    Eliciting a Robust Anticancer Immune Response

    Acepodia’s gamma delta (γδ)2 T cell program harnesses the unique properties of γδ2 T cells to develop a new class of off-the-shelf allogeneic cell therapies for the treatment of cancer. γδ2 T cells have characteristics of both the innate and adaptive immune systems that make them an ideal chassis for the development of cell therapies. This cell type can recognize and attack cancerous cells as well as coordinate a broad antitumor immune response by recruiting other immune factors and cells to the site of disease. γδ2 T cells have also been shown to preferentially traffic to distinct tissues and could be ideally suited for more targeted treatment of certain types of cancers.

  • oNK Cells
    TECHNOLOGY

    oNK Cells

    Amplified Natural Killer Cells for Off-the-Shelf Cancer-Killing Potential

    oNK cells are a proprietary natural killer (NK) cell line that is derived from the 1-2% of NK cells that have enhanced cytotoxic properties through their over expression of activation receptors and very low expression of inhibitory receptors. oNK cells can be augmented using established and novel technologies to target and engage solid tumors and hematological malignancies.

PIPELINE

ACC-γδ2 T

Program
Discovery
Preclinical
Phase I
Phase II
ACE1831
CD20 Targeting, ACC-γδ2 T Cell Therapy
Phase I ​
ACE2016
EGFR Targeting, ACC-γδ2 T Cell Therapy
Preclinical ​
ACE1708
PD-L1 Targeting, ACC-γδ2 T Cell Therapy
Discovery ​
ACE1975
Target undisclosed, ACC-γδ2 T Cell Therapy
Discovery ​
ACE2023
Target undisclosed, ACC-γδ2 T Cell Therapy
Discovery ​

ACC-oNK

Program
Discovery
Preclinical
Phase I
Phase II
ACE1702
HER2 Targeting, ACC-oNK Cell Therapy
Phase I ​